Science Signaling

Review18 Oct 2022

Overcoming metabolic adaptations in cancer

Reviews28 Sep 2021

Science Signaling

Volume 15
Issue 756
18 Oct 2022

ONLINE COVER This week, Udayasuryan et al. show that infection of normal and malignant pancreatic cells with the oral commensal microbe Fusobacterium nucleatum induces cytokine release that promotes migration and invasion by the cancer cells. In the pseudocolored scanning electron microscopy image, F. nucleatum (orange) are seen binding to and invading pancreatic cancer cells (purple).

Credit: Udayasuryan et al./Science Signaling

ReviewBy

Deborah Y. Moss
Christopher McCann
et al.

Rerouting the drug response: Overcoming metabolic adaptation in KRAS-mutant cancers

Research ArticleBy

Barath Udayasuryan
Raffae N. Ahmad
et al.

Fusobacterium nucleatum induces proliferation and migration in pancreatic cancer cells through host autocrine and paracrine signaling

Editors' ChoiceBy

Wei Wong

Taking mitochondria to heart

View table of contents

Research

18 Oct 2022

Fusobacterium nucleatum induces proliferation and migration in pancreatic cancer cells through host autocrine and paracrine signaling

4 Oct 2022

Viperin impairs the innate immune response through the IRAK1-TRAF6-TAK1 axis to promote Mtb infection

Xinying Zhou
Zelin Zhang
et al.

4 Oct 2022

The kinase PLK1 promotes the development of Kras/Tp53-mutant lung adenocarcinoma through transcriptional activation of the receptor RET

Yifan Kong
Derek B. Allison
et al.

27 Sep 2022

Mutations in protein kinase Cγ promote spinocerebellar ataxia type 14 by impairing kinase autoinhibition

Caila A. Pilo
Timothy R. Baffi
et al.

27 Sep 2022

TRAF3 enhances type I interferon receptor signaling in T cells by modulating the phosphatase PTPN22

Emma L. Hornick
Alicia M. Wallis
et al.

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